Best Medical Practice Management Software 2026

Medical practice management software streamlines scheduling, billing, and patient care for healthcare practices.

Quick Comparison

SoftwareBest ForStarting PriceKey Feature
AthenahealthLarge practicesCustomRevenue cycle
DrChronoSmall practices$199/moiPad-first
KareoBilling focus$110/moRCM
AdvancedMDSpecialtyCustomCustomization
SimplePracticeTherapists$29/moMental health

1. Athenahealth — Enterprise Choice

Price: Custom pricing

Athenahealth offers comprehensive practice management.

Features

  • ✅ Practice management
  • ✅ EHR
  • ✅ Revenue cycle management
  • ✅ Patient engagement
  • ✅ Care coordination
  • ✅ Analytics

Best For: Large practices, health systems.


2. DrChrono — Best for Small Practices

Price: $199-499/month

DrChrono offers modern, iPad-first design.

Features

  • ✅ EHR
  • ✅ Practice management
  • ✅ Medical billing
  • ✅ Patient portal
  • ✅ Telehealth
  • ✅ E-prescribing

Best For: Small-medium practices, modern workflows.


3. Kareo — Best for Billing

Price: $110-437/month

Kareo focuses on revenue cycle management.

Features

  • ✅ Practice management
  • ✅ Billing & RCM
  • ✅ Patient engagement
  • ✅ Telehealth
  • ✅ Managed billing option

Best For: Practices prioritizing billing efficiency.


4. AdvancedMD — Best Customization

Price: Custom pricing

AdvancedMD offers specialty-specific solutions.

Features

  • ✅ Customizable EHR
  • ✅ Practice management
  • ✅ Billing
  • ✅ Patient experience
  • ✅ Telemedicine
  • ✅ Reporting

Best For: Specialty practices, large groups.


5. SimplePractice — Best for Therapists

Price: $29-99/month

SimplePractice is designed for mental health professionals.

Features

  • ✅ Scheduling
  • ✅ Telehealth
  • ✅ Billing & insurance
  • ✅ Client portal
  • ✅ Documentation
  • ✅ HIPAA compliant

Best For: Therapists, counselors, mental health.


Feature Comparison

FeatureAthenaDrChronoKareo
EHR
Billing✅ Best
Patient portal
Telehealth
Mobile✅ Best

Our Recommendations

NeedChoose
EnterpriseAthenahealth
Small practiceDrChrono
Billing focusKareo
SpecialtyAdvancedMD
Mental healthSimplePractice


Last updated: January 2026